He looks like someone told him Michael Moore is coming over.
The true story of this picture is far funnier than any caption I could have come up with:
When the reporter asked for "a very quick follow-up", Bush cut him off by thanking the press corps and telling the reporter "No you may not," as he strode towards a set of double doors leading out of the room.
The only problem was that they were locked.
"I was trying to escape. Obviously, it didn't work," Bush quipped, facing reporters again until an aide rescued him by pointing to him towards the correct door.