South Carolina, 1832:

The Ordinance of Nullification declared the Tariff of 1828 and 1832 null and void within the state borders of South Carolina. It began the Nullification Crisis. Passed by a state convention on November 24, 1832, it led, on December 10, to President Andrew Jackson's proclamation against South Carolina, the Nullification Proclamation of 1832, which sent a naval flotilla and a threat of sending government ground troops to enforce the tariffs. In the face of the military threat, and following a Congressional revision of the tariff, South Carolina repealed the ordinance.

So lost that one. Lesson learned, right? South Carolina, 1860:

We, the People of the State of South Carolina, in Convention assembled do declare and ordain, and it is hereby declared and ordained, That the Ordinance adopted by us in Convention, on the twenty-third day of May in the year of our Lord One Thousand Seven hundred and eight eight, whereby the Constitution of the United State of America was ratified, and also all Acts and parts of Acts of the General Assembly of this State, ratifying amendment of the said Constitution, are here by repealed; and that the union now subsisting between South Carolina and other States, under the name of “The United States of America,” is hereby dissolved

That worked out well, huh? Still, lesson surely learned now right? South Carolina, 2013:

The South Carolina state House passed a bill Wednesday that declares President Obama’s Patient Protection and Affordable Care Act to be “null and void,” and criminalizes its implementation.

So, hard to believe that South Carolina's "intellectual" legacies would pass up a chance to kill the American government once and for all.

[cross-posted at Firedoglake]